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Folate Deficiency Anaemia is
a type of megaloblastic anaemia caused by insufficient folate, also
known as vitamin B9. Folate is essential for DNA synthesis and
the production of healthy red blood cells. When the body lacks enough folate,
red blood cells may become unusually large, immature, and less effective at
carrying oxygen.
Common causes include
inadequate dietary intake, poor absorption, increased nutritional
requirements during pregnancy, excessive alcohol consumption, and
certain medications that interfere with folate metabolism. Symptoms may
develop gradually and can include persistent tiredness, weakness, pale skin,
shortness of breath, dizziness, headaches, and difficulty concentrating. Unlike
vitamin B12 deficiency, folate deficiency usually does not cause
neurological symptoms.
Diagnosis commonly involves a complete blood count, blood smear examination,
and measurement of folate and vitamin B12 levels. Identifying the
underlying cause is important because similar blood changes can occur
with other nutritional deficiencies.
Treatment generally involves
improving dietary folate intake and taking prescribed folic acid supplements.
Foods rich in folate include leafy green vegetables, beans, lentils, citrus
fruits, and fortified cereals. Vitamin B12 deficiency should be
excluded before folic acid treatment because folic acid may improve anaemia
while allowing neurological complications of untreated B12 deficiency to
progress. Early diagnosis and appropriate treatment usually lead to good
recovery.