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Chronic Liver Disease (CLD)
refers to persistent damage and inflammation of the liver lasting for months or
years. Over time, repeated injury can cause fibrosis, where healthy liver
tissue is gradually replaced by scar tissue. Advanced fibrosis may progress to
cirrhosis, impairing essential liver functions.
Common causes include chronic
hepatitis B or C infections, alcohol-related liver injury, metabolic
dysfunction-associated steatotic liver disease (MASLD), autoimmune liver
disorders, and certain inherited conditions. Some people remain symptom-free
during the early stages, while others may experience fatigue, poor appetite,
nausea, abdominal discomfort, or unexplained weight changes.
As the disease advances, jaundice,
swelling of the abdomen or legs, easy bruising, itching, confusion,
and gastrointestinal bleeding may develop. Diagnosis generally involves
medical history, physical examination, liver function tests, viral screening,
imaging studies, and sometimes liver biopsy or non-invasive fibrosis
assessment.
Treatment depends on the
underlying cause and disease severity. Antiviral medicines may be used for chronic viral hepatitis, while lifestyle changes can help manage fatty liver
disease and alcohol-related damage. Avoiding alcohol and unnecessary medicines
that may affect the liver is important.
Regular monitoring can help
identify complications such as portal hypertension, liver failure,
and liver cancer early. Timely diagnosis and appropriate treatment may
slow disease progression and preserve liver function.