Chronic Liver Disease

Chronic Liver Disease (CLD) refers to persistent damage and inflammation of the liver lasting for months or years. Over time, repeated injury can cause fibrosis, where healthy liver tissue is gradually replaced by scar tissue. Advanced fibrosis may progress to cirrhosis, impairing essential liver functions.

Common causes include chronic hepatitis B or C infections, alcohol-related liver injury, metabolic dysfunction-associated steatotic liver disease (MASLD), autoimmune liver disorders, and certain inherited conditions. Some people remain symptom-free during the early stages, while others may experience fatigue, poor appetite, nausea, abdominal discomfort, or unexplained weight changes.

As the disease advances, jaundice, swelling of the abdomen or legs, easy bruising, itching, confusion, and gastrointestinal bleeding may develop. Diagnosis generally involves medical history, physical examination, liver function tests, viral screening, imaging studies, and sometimes liver biopsy or non-invasive fibrosis assessment.

Treatment depends on the underlying cause and disease severity. Antiviral medicines may be used for chronic viral hepatitis, while lifestyle changes can help manage fatty liver disease and alcohol-related damage. Avoiding alcohol and unnecessary medicines that may affect the liver is important.

Regular monitoring can help identify complications such as portal hypertension, liver failure, and liver cancer early. Timely diagnosis and appropriate treatment may slow disease progression and preserve liver function.