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Antiphospholipid Syndrome(APS) is an autoimmune condition in which the immune system produces antibodies that mistakenly target proteins associated with phospholipids, substances present in cell membranes. These antibodies can increase the tendency of blood to clot inside veins or arteries. APS may affect people of any age and can occur independently or alongside other autoimmune diseases, particularly systemic lupus erythematosus.

Common complications include deep vein thrombosis, pulmonary embolism, stroke, transient ischemic attacks, and heart-related blood clots. Women with APS may experience recurrent miscarriages, premature delivery, or other pregnancy complications. Some individuals may have low platelet counts or skin changes caused by impaired blood circulation.

Diagnosis generally involves evaluating a person's medical history, clinical symptoms, and laboratory tests for antiphospholipid antibodies. Because these antibodies can occasionally appear temporarily, testing is usually repeated after an appropriate interval to confirm persistent positivity.

Treatment focuses on reducing the risk of future clot formation. Anticoagulant medicines may be recommended for individuals who have experienced blood clots, while pregnant patients may require carefully monitored preventive treatment. Regular medical follow-up is important for managing risk factors and preventing complications. Early recognition and appropriate management can significantly improve long-term outcomes for people living with APS.