Platelet Disorders

Platelet Disorders are conditions that affect the number, function, or production of platelets, the blood cells responsible for forming clots and preventing excessive bleeding. These disorders can result in either too few platelets, known as thrombocytopenia, or too many platelets, called thrombocytosis. In some cases, platelet numbers may be normal, but their function is impaired.

Common causes include bone marrow disorders, autoimmune diseases, infections, certain medications, nutritional deficiencies, liver disease, and inherited conditions. Symptoms vary depending on the underlying problem and may include easy bruising, prolonged bleeding from minor cuts, frequent nosebleeds, heavy menstrual bleeding, or tiny red or purple spots on the skin called petechiae. Excessive platelet activity may increase the risk of abnormal blood clot formation.

Diagnosis usually involves a complete blood count, peripheral blood smear, platelet function tests, and additional investigations to identify the underlying cause. Treatment depends on the specific disorder and may include medicines, platelet transfusions, nutritional supplementation, treatment of an underlying disease, or specialized therapies.