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Leukocytosis is
a condition in which the quantity of white blood cells (WBCs) in the blood is
elevated above the usual level. White blood cells are a key part of the immune
system, helping the body fight infection, inflammation, and other damaging
diseases. Leukocytosis is not a sickness but rather a lab finding that
may be indicative of an underlying condition.
The usual suspects are bacterial
or viral infections, inflammatory disease, allergic reactions, physical stress,
some medications, smoking, and tissue injury. High WBC counts Sometimes
high WBC counts are caused by problems in the blood or bone marrow, such
as blood malignancies like leukemia. by malignancies of the blood
or bone marrow (e.g., leukemia). The type of white blood cell that is
raised may be important in pointing toward the cause. Some examples include Neutrophilia
in bacterial infections and lymphocytosis in some viral infections.
Symptoms are related to the
sickness, not to the leukocytosis. Some people may have no obvious
symptoms, and others may have a fever, fatigue, weakness, discomfort, or
evidence of infection. Diagnosis is usually made on the basis of a medical
history and a physical exam and a complete blood count (CBC) with
differential white blood cell count. Further testing might be indicated
if the elevation is persistent or unexplained.
Treatment is directed at the
underlying cause. Transient mild leukocytosis often subsides with the
improvement of the underlying illness. If the irregularities persist, further
medical examination will be needed.