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Aplastic Anaemia is
an uncommon but deadly blood condition in which the bone marrow does not make
enough healthy blood cells. This deficit can affect red blood cells,
white blood cells and platelets at the same time. Patients can
report ongoing fatigue, weakness, pale complexion, recurrent infections, fever,
easy bruising, nosebleeds or bleeding for longer than normal after minor
traumas.
It can occur when the immune system destroys stem cells in the bone marrow, but drugs, harmful chemicals, radiation, viral infections, and hereditary
disorders can also play a role. Sometimes no cause can be found, and the
condition is called 'idiopathic aplastic anaemia'.
Doctors usually diagnose it with blood tests showing low blood cell counts and a bone marrow biopsy to assess cell production. Treatment depends on the severity of the disease, age,
general health and the underlying cause. Treatment may involve supportive blood
or platelet transfusions, medications to decrease aberrant immune
activity, growth factors, or stem cell transplantation.
Early diagnosis and
treatment are critical since severe aplastic anaemia can cause major
infections, severe bleeding, and problems caused by inadequate oxygen
supply. Routine follow-up with a haematologist is important to check
blood levels, response to treatment and any problems.