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Metabolic syndrome,
also called insulin resistance syndrome, is a group of interconnected health
conditions that significantly raise the risk of coronary heart disease,
type 2 diabetes, stroke, and other serious complications. It is diagnosed
when a person has three or more of five key conditions: central or abdominal
obesity (waist circumference >40 inches in men, >35 inches in women),
high triglycerides (?150 mg/dL), low HDL cholesterol (<40 mg/dL in men,
<50 mg/dL in women), high blood pressure (?130/85 mm Hg), and elevated
fasting glucose (?100 mg/dL).
The syndrome is linked
primarily to insulin resistance, where the body doesn't respond properly
to insulin, and excess fat around the tummy. About 1 in 3 adults in the United
States has metabolic syndrome, making it very common.
Metabolic syndrome increases the chances of developing cardiovascular disease, type 2 diabetes, non-alcoholic
fatty liver disease, osteoarthritis, gout, certain cancers, and may affect
fertility. Most conditions have no visible signs except a large waistline, but high
blood sugar can cause blurred vision, increased thirst, urination, and
tiredness.
The syndrome is largely preventable and reversible through healthy lifestyle changes, including weight loss, regular physical activity, a healthy diet, and smoking cessation. Managing blood pressure, cholesterol, and blood sugar through medication when needed also reduces complications.