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Triple Vessel Disease is a severe form of coronary artery disease in which all three major coronary arteries supplying blood to the heart become significantly narrowed or blocked. These arteries include the left anterior descending artery, left circumflex artery, and right coronary artery. Reduced blood flow limits oxygen delivery to the heart muscle, increasing the risk of chest pain, heart attack, heart failure, and life-threatening cardiac complications.

The condition commonly develops due to atherosclerosis, where fatty deposits accumulate inside artery walls over time. Major risk factors include smoking, diabetes, hypertension, high cholesterol, obesity, stress, physical inactivity, and a family history of heart disease. Symptoms may include angina, breathlessness, excessive fatigue, irregular heartbeat, sweating, nausea, or discomfort spreading to the shoulders, arms, or jaw. Some individuals may experience silent ischemia without obvious warning signs.

Diagnosis usually involves ECG, stress testing, echocardiography, coronary angiography, CT angiography, and cardiac imaging studies. Treatment focuses on improving blood circulation and preventing further arterial damage. Medications such as antiplatelets, statins, nitrates, and beta-blockers are commonly prescribed. In advanced cases, coronary artery bypass grafting (CABG) is often recommended to restore blood flow effectively. Lifestyle changes, healthy eating, exercise, and regular medical follow-up are essential for long-term heart health and prevention of future complications.