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Leukemia, particularly acute lymphoblastic (ALL) and myeloid (AML), accounts for about 28-34% of cases, originating in blood and bone marrow. Brain and spinal tumors represent over 20%, while lymphomas and solid tumors like Wilms tumor and rhabdomyosarcoma follow.?
Symptoms and Diagnosis
Common signs include unexplained fever, bone pain, fatigue, weight loss, bruising, and lumps; early detection via imaging, biopsies, and blood tests improves outcomes. Risk-stratified therapies tailor treatment to prognosis, minimizing side effects.?
Treatment and Prognosis
Multimodal approaches combine chemotherapy, surgery, radiation, and immunotherapy, yielding survival advances; global disparities persist due to access issues. Ongoing research targets novel therapies for better long-term quality of life