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Polycystic Kidney Disease (PKD) is a genetic disorder where clusters of fluid-filled cysts develop within the kidneys, leading to progressive enlargement and loss of kidney function. The condition can be inherited as autosomal dominant (ADPKD), typically diagnosed in adulthood, or autosomal recessive (ARPKD), which manifests in infancy. These cysts compress normal kidney tissue, impairing its ability to filter waste, and can eventually cause chronic kidney disease or failure.

Common symptoms include high blood pressure, back or abdominal pain, blood in the urine, and frequent urinary infections. PKD may also affect other organs, causing liver cysts, heart valve problems, or vascular disorders. Diagnosis is made using imaging studies like ultrasound, CT, or MRI. While there is no definitive cure, treatment focuses on controlling symptoms, maintaining blood pressure, slowing cyst growth, and managing complications. In advanced cases, dialysis or kidney transplantation becomes necessary. Lifestyle modifications, hydration, and regular medical monitoring help improve disease outcomes and patient quality of life.?