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Rare head and neck cancer called nasopharyngeal carcinoma starts in the nasopharynx, the top section of the throat behind the nose. It has a unique aetiology and features unlike most head and neck malignancies. The most common type is non-keratinizing squamous cell carcinoma.
Epstein-Barr Virus (EBV) infection is among the most potent risk factors. Genetic predisposition, consumption of preserved or salted foods, and exposure to environmental pollution are additional contributing factors. It is more typical in several areas, including Southern China, Southeast Asia, and portions of North Africa.
Symptoms typically appear late and may include nasal congestion or bleeding, frequent ear infections, lumps in the neck, headaches, and facial paralysis. It can be challenging to identify these symptoms early on, as they often mimic common ailments.
The diagnosis calls for nasal endoscopy, biopsy, and MRI or PET-CT imaging. Radiation is the primary treatment since the location of the nasopharynx dictates it. It is usually paired with chemotherapy. The complexity of the area influences the lower frequency of surgery.
Early diagnosis greatly affects outcomes. For high-risk groups, particularly those with a family history or EBV exposure, regular visits are absolutely essential.