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Childhood leukaemia is
the most common type of cancer affecting children and develops when the bone
marrow produces abnormal white blood cells. These cancerous cells multiply
rapidly, crowding out healthy blood cells and reducing the body's ability to
fight infections, carry oxygen, and control bleeding. The two main types are acute
lymphoblastic leukaemia (ALL), which is the most common, and acute
myeloid leukaemia (AML).
Symptoms may include persistent
fever, fatigue, pale skin, frequent infections, easy bruising or bleeding,
swollen lymph nodes, bone or joint pain, weight loss, and enlarged liver
or spleen. Since these symptoms can resemble common childhood illnesses,
early medical evaluation is essential for timely diagnosis.
Diagnosis involves a complete
blood count (CBC), peripheral blood smear, bone marrow aspiration,
immunophenotyping, genetic testing, and imaging studies when needed. These
tests help determine the type and stage of the disease, guiding treatment
decisions.
Treatment typically includes
chemotherapy, targeted therapy, immunotherapy, radiation therapy in selected
cases, and stem cell transplantation for high-risk patients. Advances in paediatric cancer care have significantly improved survival rates. Regular follow-up,
supportive care, nutritional support, and infection prevention are
essential to ensure successful treatment outcomes and enhance the child's
quality of life during recovery.