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Autoimmune Haemolytic Anaemia is a rare blood disorder in which the body's
immune system mistakenly attacks and destroys its own red blood cells. This
premature destruction, known as haemolysis, reduces the number of healthy red
blood cells available to carry oxygen throughout the body, leading to anaemia. The
condition may develop on its own (primary) or occur alongside other illnesses
such as autoimmune diseases, infections, certain cancers, or as a
reaction to medications. Autoimmune Haemolytic Anaemia is commonly
classified into warm and cold types, depending on the temperature at which the
harmful antibodies become active. Symptoms often include fatigue, weakness,
pale skin, shortness of breath, rapid heartbeat, dizziness, dark urine, and
jaundice.
Diagnosis involves blood
tests such as a complete blood count, reticulocyte count, bilirubin levels,
lactate dehydrogenase (LDH), haptoglobin, and the direct Coombs (direct
antiglobulin) test. Treatment depends on the severity and underlying cause and
may include corticosteroids, immunosuppressive medicines, monoclonal
antibody therapy, blood transfusions, or splenectomy in selected cases.
With early diagnosis, appropriate treatment, and regular medical follow-up,
many patients can successfully control the condition and maintain a good
quality of life.