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Postoperative malabsorption
occurs when surgical intervention in the gastrointestinal tract
compromises the body’s ability to absorb essential nutrients.
This condition commonly follows procedures like bowel resection, bariatric
surgery, or removal of the terminal ileum, where critical absorption sites are
lost. The small intestine normally absorbs proteins, carbohydrates, fats,
vitamins, and minerals; when its length or mucosal surface is
reduced—particularly in short bowel syndrome—nutrient uptake declines
significantly.
Key causes include loss of
absorptive surface area, altered intestinal motility, bile acid malabsorption,
and bacterial overgrowth in the remaining gut. Patients typically present with chronic
diarrhea, steatorrhea (fatty stools), unintended weight loss, bloating, and
fatigue. Over time, deficiencies in fat-soluble vitamins (A, D, E, K),
vitamin B12, iron, calcium, and magnesium may develop, increasing risks of osteoporosis,
anemia, and neurological complications.
Diagnosis involves stool
tests for fat content, blood work for nutrient levels, and
sometimes imaging or breath tests. Treatment focuses on dietary
modification—small, frequent meals low in fat but high in easily digestible
proteins—and aggressive supplementation of missing nutrients. In severe
short bowel syndrome, parenteral nutrition may be required. Medications
like bile acid binders, antibiotics for bacterial overgrowth, and
motility-modifying drugs (e.g., trimebutine) can also help. Early nutritional
intervention and long-term monitoring are essential to prevent
complications and improve quality of life after gastrointestinal surgery.