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Dupuytren’s Contracture is a degenerative disease of the hand that affects the connective tissue beneath the skin of the palm (the fascia). The tissue gradually thickens and produces nodules or cords that pull one or more fingers—usually the ring and little fingers—toward the palm. The ailment usually progresses slowly and is generally painless, but it can severely impede hand function and the ability to grip.

The cause is not known, but there is a strong genetic component, and it is more common in elderly adults, particularly men of Northern European heritage. Risk factors include diabetes, smoking, alcohol consumption, and certain medical problems.
Early symptoms are tiny bumps in the palm that may slowly progress into tight bands. The diagnosis is typically made through a physical examination, including the "tabletop test."

Treatment depends upon severity. Mild cases might just be watched, whereas severe cases might require a needle aponeurotomy, enzyme injections, or surgery to loosen the constricted tissue. Early management can help preserve hand mobility and function.