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Bone tumors are
abnormal growths that arise within bone tissue and can be benign or malignant,
with differing behavior, prognosis, and treatment approaches. Primary bone
cancers — most commonly osteosarcoma, chondrosarcoma, and Ewing
sarcoma — originate in bone cells and are distinct from metastatic lesions
that spread to bone from other organs. Benign lesions such as osteochondromas
or giant cell tumors may cause pain, swelling, or fractures by weakening bone,
but often remain localized. Presentation frequently includes persistent bone
pain (worse at night), localized swelling, reduced function, and pathologic
fractures; symptoms and age distribution vary by tumor type, with osteosarcoma
and Ewing sarcoma more common in children and adolescents, while chondrosarcoma
typically affects adults.
Diagnosis combines imaging
(X-ray, MRI, CT, bone scan) and biopsy for histologic
classification following WHO categories, which guide staging and treatment
planning. Management is multidisciplinary: surgery is central for local
control, chemotherapy is standard for osteosarcoma and Ewing
sarcoma, and radiation is used selectively or for palliation; prognosis
depends on tumor type, stage, location, and response to therapy.
Regular follow-up monitors recurrence and functional recovery.