Neuroendocrine Tumors (NETs)

Neuroendocrine tumors (NETs) tumors can develop in the stomach, intestines, pancreas, lungs, appendix, or other organs, and their behavior depends on the site and how fast they grow. Some NETs release hormones and cause symptoms such as flushing, diarrhea, wheezing, abdominal pain, or low blood sugar, while others stay silent for a long time and are found only after imaging or laboratory tests. Because the signs can resemble common digestive or respiratory problems, diagnosis is sometimes delayed.

Doctors usually evaluate NETs with blood tests, scans, endoscopy, biopsy, and sometimes specialized hormone markers. Treatment may include surgery, observation, somatostatin analog medicines, targeted therapy, chemotherapy, or peptide receptor radionuclide therapy, depending on tumor type and spread. Many NETs grow slowly, but some are more aggressive, so long-term follow-up is important. Early detection helps guide treatment and can improve outcomes, especially when the tumor is localized.