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Antiphospholipid Syndrome (APS) is an autoimmune illness marked by the development of antiphospholipid antibodies, which elevate the risk of thrombosis and problems associated with pregnancy. In APS, the immune system incorrectly attacks phospholipid-binding proteins, which messes with normal coagulation pathways. This can cause deep vein thrombosis, stroke, or pulmonary embolism. In women of reproductive age, APS is a major factor contributing to recurrent pregnancy loss, hypertension, intrauterine growth restriction, and stillbirth.

Diagnosis often requires both clinical criteria (such as a history of thrombosis or pregnancy morbidity) and laboratory results, such as consistently positive tests for lupus anticoagulant, anticardiolipin antibodies, or anti-?? glycoprotein I antibodies. Management is all about stopping blood clots from forming and making pregnancy go well. Anticoagulants like heparin or low-dose aspirin are often used to treat people with APS, especially when they are pregnant.
Early diagnosis and the right treatment make a big difference in the outcome.

Long-term follow-up is necessary since APS can be a long-term condition that needs ongoing care. For the best results, people with this condition generally need care from both haematologists and obstetricians.