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Poor ovarian response (POR) during in vitro fertilisation (IVF) cycles means that the ovaries don't respond as well to hormonal stimulation, which means that fewer eggs are collected than expected. This disease has a big effect on the success rates of IVF since both the number and quality of eggs are important for fertilisation and embryo growth.

People with POR frequently have a lower ovarian reserve, are older than average, have hereditary factors, or have had surgery on their ovaries in the past. Women with POR may need to take additional fertility drugs, yet they may still not get many eggs, which makes therapy harder. Clinically, the diagnosis is made when fewer than three to four follicles form despite appropriate stimulation methods.

Management techniques encompass personalised stimulation regimens, the use of adjuvant medicines such as growth hormone or androgens, and alternative procedures like light stimulation or natural cycle IVF. In extreme situations, donor eggs may be used to increase the odds of getting pregnant.

To plan treatment, it's important to find women who are at risk early on by testing their anti-Müllerian hormone (AMH) levels and antral follicle count. Even though a weak ovarian response can make things harder, new developments in reproductive medicine and personalised treatments have helped many women have successful pregnancies, giving them hope and better prospects of becoming parents even with lower ovarian function.