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Gastro-oesophageal reflux
disease is a long-term problem where stomach contents, including
acid, keep flowing back into the oesophagus. This reflux happens because
the lower oesophageal sphincter (LES), a muscle valve that ordinarily
keeps stomach contents from moving back, is weak or not relaxing properly. When
acid stays in the oesophagus for a long time, it can irritate the
lining, causing symptoms including heartburn, regurgitation, chest pain,
and a foul taste in the mouth.
People of all ages can
develop GERD, but being overweight, pregnant, smoking, and eating
foods that exacerbate it, such as spicy or fatty meals, coffee, and alcohol,
are all risk factors. In certain instances, individuals may present with
extra-oesophageal manifestations, including chronic cough, hoarseness, or
throat irritation.
Diagnosis is frequently
clinical but may be augmented by endoscopy, pH monitoring, or oesophageal
manometry in complex instances. Management emphasises lifestyle
modifications—such as weight loss, dietary alterations, and avoiding
late meals—concomitant with pharmaceutical interventions, often proton
pump inhibitors (PPIs) or H? receptor antagonists.
If not addressed, GERD
can cause problems, including oesophagitis, strictures, or Barrett's
oesophagus, which is a condition where the oesophagus lining changes and
can lead to cancer. Recognising and treating problems early on greatly improves
the quality of life and lowers long-term dangers.